蓝萼甲素

分析标准品,HPLC≥98%

Glaucocalyxin A

CAS号：79498-31-0

分子式：C20H28O4

分子量：332.43

MDL：MFCD00915351

产品介绍

熔点：219.5-220.5℃ (ethy l ether )

沸点：513.4℃ at 760 mmHg

比旋光度：(c, 0.34 in MeOH)-170

外观：白色粉末

溶解性：Very slightly soluble (0.96 g/L) (25 ℃)

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(9篇)

9. [IF=5.5] Ling Wang et al."Thioredoxin reductase inhibition and glutathione depletion mediated by glaucocalyxin A promote intracellular disulfide stress in gastric cancer cells."FEBS Journal.2024 Oct;:

8. [IF=2.6] Hong Xin et al."Glaucocalyxin A delays the progression of OA by inhibiting NF-κB and MAPK signaling pathways."Journal of Orthopaedic Surgery and Research".2024 Dec;19(1):1-13

7. [IF=3.434] Zhu Weidong et al."Glaucocalyxin A Attenuates IL-1β-Induced Inflammatory Response and Cartilage Degradation in Osteoarthritis Chondrocytes via Inhibiting the Activation of NF-κB Signaling Pathway."Dis Markers. 2022;2022:6516246

6. [IF=2.629] Piao Yihua et al."Glaucocalyxin A Attenuates Allergic Responses by Inhibiting Mast Cell Degranulation through p38MAPK/NrF2/HO-1 and HMGB1/TLR4/NF-κB Signaling Pathways."Evid-Based Compl Alt. 2021;2021:6644751

5. [IF=3.647] Jiasheng Chen et al."Glaucocalyxin A induces cell cycle arrest and apoptosis via inhibiting NF-κB/p65 signaling pathway in melanoma cells."Life Sci. 2021 Apr;271:119185

4. [IF=4.36] Meisong Zhu et al."Glaucocalyxin A suppresses osteoclastogenesis induced by RANKL and osteoporosis induced by ovariectomy by inhibiting the NF-κB and Akt pathways."J Ethnopharmacol. 2021 Aug;276:114176

3. [IF=4.858] Wenfeng Lin et al."Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells."Int J Biol Sci. 2018; 14(4): 418–426

2.  朴艺花,宋艺兰,王知广,姜京植,李莉,徐畅,朴颖,朴红梅,延光海.蓝萼甲素通过抑制HMGB1/TLR4/NF-κB信号通路减轻肥大细胞脱颗粒引起的过敏反应[J].药学学报,2021,56(01):201-207.

1.  朴艺花,王知广,姜京植,王重阳,朴红梅,延光海.蓝萼甲素通过HMGB1/TLR4/NF-κB信号通路缓解卵清蛋白诱导的哮喘小鼠气道炎症[J].国际药学研究杂志,2020,47(09):738-744.

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