胡桃醌

分析标准品,HPLC≥98%

5-Hydroxy-1,4-naphthalenedione

CAS号：481-39-0

分子式：C10H6O3

分子量：174.16

MDL：MFCD00001684

别名：5-羟基-1,4-萘醌;5-羟基-1,4-萘二酮;5-羟基-4-萘醌;黑粟素

产品介绍

Juglone是一种从黑胡桃Juglans regia中发现的黄色染料，有抗菌作用。

熔点：161-163℃

沸点：385.8 ℃ at 760 mmHg

外观：黄色针状结晶

溶解性：Ethanol:10mg/mL(57.42mM;Needultrasonic;DMSO can inactivate Juglone's activity)

敏感性：对光敏感

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(22篇)

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18. [IF=3.7] Jian Zhong et al."Juglone triggers apoptosis of non-small cell lung cancer through the reactive oxygen species -mediated PI3K/Akt pathway."PLoS One".2024 May;19(5):e0299921

17. [IF=4.8] Yu Xingzhi et al."4,4′-methylenediphenol reduces Aβ-induced toxicity in a Caenorhabditis elegans model of Alzheimer’s disease."Frontiers in Aging Neuroscience".2024 May;16:

16. [IF=4.8] Yu Xingzhi et al."P-hydroxybenzald ehyde protects Caenorhabditis elegans from oxidative stress and β-amyloid toxicity."Frontiers in Aging Neuroscience".2024 May;16:

15. [IF=1.8] Xue Wang et al."Integrated UHPLC-Q-Orbitrap-MS/MS Method and Network Pharmacology for Exploring the Active Components and Potential Mechanisms of Neuroprotective Effect of the n-Butanol Part of Mume Flos."Natural Product Communications.10.1177/1934578X241

14. [IF=4.3] Yi Jiang et al."Shading in fruit changes the polyphenol accumulation of pellicle by regulating activity of key enzymes and expression of their gene related polyphenol anabolism of Juglans sigillata Dode."SCIENTIA HORTICULTURAE".2024 Apr;329:113017

13. [IF=7.8] Chaweewan Sirakawin et al."SKN-1/NRF2 upregulation by vitamin A is conserved from nematodes to mammals and is critical for lifespan extension in Caenorhabditis elegans."AGING CELL.2023 Dec;:e14064

12. [IF=8.2] Yangli Wan et al."Antibacterial activity of juglone @ chitosan nanoemulsion against Staphylococcus aureus and its effect on pork shelf life."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.2023 Dec;253:127273

11. [IF=2.7] Xiongfei Shi et al."Ethyl acetate extract of Gastrodia elata protects Caenorhabditis elegans from oxidative stress and amyloid β peptide toxicity."Experimental and Therapeutic Medicine.2023 Aug;26(2):1-12

10. [IF=8.022] Hui Zou et al."Effective anti-inflammatory phenolic compounds from dandelion: identification and mechanistic insights using UHPLC-ESI-MS/MS, fluorescence quenching and anisotropy, molecular docking and dynamics simulation."Food Science and Human Wellness.

9. [IF=6.208] Yangli Wan et al."Antibacterial Activity of Juglone Revealed in a Wound Model of Staphylococcus aureus Infection."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2023 Jan;24(4):3931

8. [IF=5.561] Yingying Cai et al."Juglone Inhibits Listeria monocytogenes ATCC 19115 by Targeting Cell Membrane and Protein."Foods.2022 Jan;11(17):2558

7. [IF=5.81] Yihui Yin et al.The Molecular Mechanism of Antioxidation of Huolisu Oral Liquid Based on Serum Analysis and Network Analysis.Front Pharmacol. 2021 Nov 1;12:710976

6. [IF=3.512] Yahong Chen et al."Identification of Potential Human Ryanodine Receptor 1 Agonists and Molecular Mechanisms of Natural Small-Molecule Phenols as Anxiolytics."Acs Omega. 2021;XXXX(XXX):XXX-XXX

5. [IF=3.943] Yongzhi Hua et al."Juglone regulates gut microbiota and Th17/Treg balance in DSS-induced ulcerative colitis."Int Immunopharmacol. 2021 Aug;97:107683

4. [IF=4.411] Fang Sheng et al."The Analysis of Phenolic Compounds in Walnut Husk and Pellicle by UPLC-Q-Orbitrap HRMS and HPLC."Molecules. 2021 Jan;26(10):3013

3. [IF=6.953] Lin Zhou et al."Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans."Int J Biol Macromol. 2018 Jul;113:1015

2.  Zhou, Lin, et al. "Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans." International journal of biological macromolecules 113 (2018): 1015-1023.https:##doi.org/10.1016/j.ijbiomac.2018.03.014

1.  张立华, 李妍, 张沛,等. 干燥方式对核桃青皮胡桃醌含量与抑菌性能的影响[J]. 食品工业科技, 2017, 38(10):141-145.

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