粉防己碱

分析标准品,HPLC≥98%

Tetrandrine

CAS号：518-34-3

分子式：C38H42N2O6

分子量：622.75

MDL：MFCD08689909

别名：汉防己碱；汉防己甲素

产品介绍

 Tetrandrine (NSC-77037; d-Tetrandrine) 是一种双苯基异喹啉生物碱，抑制电压门控钙离子通道 (ICa) 和 Ca2+ 激活的钾离子通道。

熔点：219-222℃

沸点：710.5℃ at 760 mmHg

比旋光度：285 º (c=1, CHCl3)

外观：无色针状结晶(乙mi)

溶解性：DMSO:5mg/mL(8.03 mM;Needultrasonic and warming)

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(21篇)

21. [IF=4] Tan Lihua et al."In-vitro Evaluation of p-Sulfonatocalix[n] arenes (SCnA) as Novel Excipients Using a Vectorized BCS Approach."AAPS PHARMSCITECH.2025 Oct;26(7):1-17

20. [IF=1.3] Yu Wang et al."Tetrandrine Improves Ventricular Remodeling and Inflammation via Inhibition of the MAPK/NF-κB Pathway."International Heart Journal.

19. [IF=2.5] Li Chen et al."Optimization of Extraction Process of Total Alkaloids from Thalictrum delavayi Franch. and Their Therapeutic Potential on Pulmonary Infection Caused by Klebsiella pneumoniae and Escherichia coli."Separations.2024 Jul;11(7):210

18. [IF=4.7] Xu Zhang et al."Rhein: A potent immunomodulator empowering largemouth bass against MSRV infection."FISH & SHELLFISH IMMUNOLOGY.2024 Jan;144:109284

17. [IF=3.3] Zhang Xueyan et al."A (Traditional Chinese Medicine) TCM-Inspired Doxorubicin Resistance Reversing Strategy: Preparation, Characterization, and Application of a Co-loaded pH-Sensitive Liposome."AAPS PHARMSCITECH.10.1208/s12249-023-02630-8

16. [IF=7.419] Bichen Li et al."Total alkaloids in Stephania tetrandra induce apoptosis by regulating BBC3 in human non–small cell lung cancer cells."BIOMEDICINE & PHARMACOTHERAPY.2023 Jun;162:114635

15. [IF=5.988] Jun Li et al."Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach.."Frontiers in Pharmacology.2022 Oct;13:999950-999950

14. [IF=3.024] Xuan Yu et al."An innovative extraction strategy for herbal medicine by adopting p-sulphonatocalix[6]/[8]arenes."PHYTOCHEMICAL ANALYSIS

13. [IF=3] Qu  Lala et al."Phenotypic assessment and ligand screening of ETA/ETB receptors with label-free dynamic mass redistribution assay."N-S Arch Pharmacol. 2020 Jun;393(6):937-950

12. [IF=4.411] Dan Liao et al."Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression."Molecules. 2019 Jan;24(23):4383

11. [IF=4.769] Zhenzhong Yang et al."Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe."J Pharm Anal. 2020 Nov;:

10. [IF=4.939] Mengjuan Jiang et al."Reduction-sensitive Paclitaxel Prodrug Self-assembled Nanoparticles with Tetrandrine Effectively Promote Synergistic Therapy Against Drug-sensitive and Multidrug-resistant Breast Cancer."Mol Pharmaceut. 2017;14(11):3628–3635

9. [IF=5.64] Wu  Dousheng et al."Oleanolic Acid Induces the Type III Secretion System of Ralstonia solanacearum."Front Microbiol. 2015 Dec;0:1466

8.  Yang, Zhenzhong, et al. "Deciphering bioactive compounds of complex natural products by tandem mass spectral molecular networking combined with an aggregation-induced emission based probe." Journal of Pharmaceutical Analysis (2020).https:##doi.org/10.1016/

7.  Mengjuan Jiang, Ruoshi Zhang, Yingli Wang, Wenna Jing, Ying Liu, Yan Ma, Bingjun Sun, Menglin Wang, Peizhuo Chen, Hongzhuo Liu, and Zhonggui He,Reduction-sensitive Paclitaxel Prodrug Self-assembled Nanoparticles with Tetrandrine Effectively Promote Synergi

6.  何婉婉 张建逵 李云静 康廷国.北豆根药材粉末色泽与有效成分的相关性[J].中国实验方剂学杂志 2017 23(05):57-62.

5.  何婉婉 张建逵 李云静 康廷国.北豆根显微特征指数与化学成分相关性[J].中国实验方剂学杂志 2017 23(01):42-46.

4.  胡筱希  朱荣  唐新 等. 响应曲面法优化防己中汉防己甲素及汉防己乙素的提取工艺[J]. 中国民族民间医药  2020  v.29;No.366(01):29-34.

3.  张克清, 戴珍, 李彦萍. 粉防己碱激活Akt/GSK-3b信号通路保护心肌I/R大鼠研究[J]. 新中医, 2018, 050(009):12-17.

2.  郭孝玉, 张潇月, 李奇勇,等. 粉防己碱对铜绿微囊藻的化感作用[J]. 三明学院学报, 2017, 034(006):57-61.

1.  杨敬宁, 张燕, 王敏,等. 粉防己碱对胡蜂毒素致多器官功能障碍综合征大鼠的保护作用[J]. 中国工业医学杂志, 2018, 31(05):12-13+83.

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