大黄素-8-β-D-吡喃葡萄糖苷

分析标准品,HPLC≥98%

Emodin-8-glucoside

CAS号：23313-21-5

分子式：C21H20O10

分子量：432.38

MDL：MFCD01725365

产品介绍

熔点：219-220 ℃

沸点：798.7℃at760mmHg

外观：黄色粉末

溶解性：可溶于甲醇、乙醇、DMSO等有机溶剂。

储存条件：2-8℃

注意：部分产品我司仅能提供部分信息，我司不保证所提供信息的权威性，仅供客户参考交流研究之用。

参考文献(38篇)

38. [IF=5.7] Huang Zhiqi et al."Sanhuang Xiexin Decoction ameliorates lipid disorders in obese mice via inducing browning of white adipose tissue and activating brown adipose tissue."Chinese Medicine.2025 Dec;20(1):1-17

37. [IF=1.3] Ze-Ye Tan et al."Correlation analysis between potential hepatotoxicity and ingredient content of polygoni multiflori caulis."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.

36. [IF=5.3] Junqi Bai et al."In-vivo metabolic profiling of the Natural products Emodin and Emodin-8-O-β-D-glucoside in rats using liquid chromatography quadrupole Orbitrap mass spectrometry."Arabian Journal of Chemistry.2024 Sep;17:105905

35. [IF=4.1] Xiaoyao Liu et al."The Water Extract of Rhubarb Prevents Ischemic Stroke by Regulating Gut Bacteria and Metabolic Pathways."Metabolites".2024 Apr;14(4):216

34. [IF=4.3] Fan Xinyu et al."A comprehensive investigation on the chemical changes of traditional Chinese medicine with classic processing technology: Polygonum multiflorum under nine cycles of steaming and sunning as a case study."ANALYTICAL AND BIOANALYTICAL CHEMIS

33. [IF=1.3] Mei Yudan et al."Chemical Profiling of Shen-Wu-Yi-Shen Tablets Using UPLC-Q-TOF-MS/MS and Its Quality Evaluation Based on UPLC-DAD Combined with Multivariate Statistical Analysis."JOURNAL OF CHROMATOGRAPHIC SCIENCE.2024 Jan;:

32. [IF=3.8] Yumiao Li et al."Optimization of the proportions of advantageous components in the hypolipidemic “bioequivalent substance system" of Jiang-Zhi-Ning and its mechanism of action."PHARMACEUTICAL BIOLOGY.10.1080/13880209.2023.2243999

31. [IF=5.545] Xueting Wang et al."On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS."Frontiers in Chemistry.2023; 11: 1158717

30. [IF=3.614] Liqing Wang et al."Discovery of the potential neuraminidase inhibitors from Polygonum cuspidatum by ultrafiltration combined with mass spectrometry guided by molecular docking."JOURNAL OF SEPARATION SCIENCE.2023 Mar;:2200937

29. [IF=3.571] Yudan Mei et al."Screening and characterization of xenobiotics in rat bio-samples after oral administration of Shen-Wu-Yi-Shen tablet using UPLC-Q-TOF-MS/MS combined with a targeted and non-targeted strategy."JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALY

28. [IF=6.656] Yanchao Xing et al."Cytochrome P450-mediated herb-drug interaction (HDI) of Polygonum multiflorum Thunb. based on pharmacokinetic studies and in vitro inhibition assays."PHYTOMEDICINE.2023 Feb;:154710

27. [IF=5.195] Qi Wang et al."Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid."JOURNAL OF ETHNOPHARMACOLOGY.2022 Oct;296:115461

26. [IF=5.811] Kong  Wei-Song et al."Beware of the Potential Risks for Polygoni Multiflori Caulis-Induced Liver Injury."Front Pharmacol. 2022 Apr;0:928

25. [IF=5.645] Huilan Yue et al."Hypoglycemic ingredients identification of Rheum tanguticum Maxim. ex Balf. by UHPLC-triple-TOF-MS/MS and interrelationships between ingredients content and glycosidase inhibitory activities."Ind Crop Prod. 2022 Apr;178:114595

24. [IF=3.743] Longfei Lin et al."Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro."Biomed Pharmacother. 2019 Dec;120:109531

23. [IF=3.935] Yanchao Xing et al."An effective strategy for distinguishing the processing degree of Polygonum multiflorum based on the analysis of substance and taste by LC-MS, ICP-OES and electronic tongue."J Pharmaceut Biomed. 2021 Oct;205:114328

22. [IF=4.142] Wang  Chenxi et al."Systematic quality evaluation of Peiyuan Tongnao capsule by offline two-dimensional liquid chromatography/quadrupole-Orbitrap mass spectrometry and adjusted parallel reaction monitoring of quality markers."Anal Bioanal Chem. 2019 Nov;4

21. [IF=0] Longfei Lin et al."Application of iTRAQ-Based Quantitative Proteomics Approach to Identify Deregulated Proteins Associated with Liver Toxicity Induced by Polygonum Multiflorum in Rats."Cell Physiol Biochem. 2017;43(5):2102-2116

20. [IF=1.902] Longfei Lin et al."Characterization of the constituents in rat plasma after oral administration of radix polygoni multiflori extracts by ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry."Biomed Chromatogr. 2015 Oct;29(10

19. [IF=1.902] Longfei Lin et al."Simultaneous determination of 14 constituents of Radix polygoni multiflori from different geographical areas by liquid chromatography–tandem mass spectrometry."Biomed Chromatogr. 2015 Jul;29(7):1048-1055

18. [IF=3] Juan HUANG et al."Chemical profiles and metabolite study of raw and processed Polygoni Multiflori Radix in rats by UPLC-LTQ-Orbitrap MSn spectrometry."Chin J Nat Medicines. 2018 May;16:375

17. [IF=4.379] Wang  Qi et al."Identification and characterization of the structure–activity relationships involved in UGT1A1 inhibition by anthraquinone and dianthrone constituents of Polygonum multiflorum."Sci Rep-Uk. 2017 Dec;7(1):1-9

16. [IF=5.645] Fangyuan Gao et al."Cyclodextrin-based ultrasonic-assisted microwave extraction and HPLC-PDA-ESI-ITMSn separation and identification of hydrophilic and hydrophobic components of Polygonum cuspidatum: A green, rapid and effective process."Ind Crop Prod. 20

15. [IF=5.81] Lin  Longfei et al."A New Perspective on Liver Injury by Traditional Chinese Herbs Such As Polygonum multiflorum: The Geographical Area of Harvest As an Important Contributory Factor."Front Pharmacol. 2017 Jun;0:349

14. [IF=5.81] Zhang  Miao et al."Interpretation the Hepatotoxicity Based on Pharmacokinetics Investigated Through Oral Administrated Different Extraction Parts of Polygonum multiflorum on Rats."Front Pharmacol. 2018 May;0:505

13. [IF=10.588] Longfei Lin et al."A novel method to analyze hepatotoxic components in Polygonum multiflorum using ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry."J Hazard Mater. 2015 Dec;299:249

12.  Lin, Longfei, et al. "Hepatotoxicity and mechanism study of chrysophanol-8-O-glucoside in vitro." Biomedicine & Pharmacotherapy 120 (2019): 109531.https:##doi.org/10.1016/j.biopha.2019.109531

11.  Lin, Longfei et al. “A New Perspective on Liver Injury by Traditional Chinese Herbs Such As Polygonum multiflorum: The Geographical Area of Harvest As an Important Contributory Factor." Frontiers in pharmacology vol. 8 349. 20 Jun. 2017, doi:10.3389/fphar.

10.  Lin, Longfei, et al. "Application of iTRAQ-based quantitative proteomics approach to identify deregulated proteins associated with liver toxicity induced by polygonum multiflorum in rats." Cellular Physiology and Biochemistry 43.5 (2017): 2102-2116.https:/

9.  汪颖舒,朱广灏,王冰,李杰荣,骆前飞,何修滢,赵佳逸,修彦凤.古法黑豆蒸晒与药典黑豆汁连续蒸对何首乌中12个成分含量的影响[J].中草药,2020,51(19):4972-4982.

8.  吴嫣艳,任会旭,冯友龙,张莉,张妤琳.安神补脑胶囊HPLC指纹图谱与3种成分含量测定方法研究[J].广东药科大学学报,2020,36(06):778-783.

7.  敏,张志,李听弦,陶彩霞,贾平,王光忠.大黄煨制前后HPLC指纹图谱的比较研究[J].时珍国医国药,2020,31(06):1361-1364.

6.  汪祺, 张茜蕙, 文海若,等. 基于肝微组织考察何首乌主要单体潜在肝毒性[J]. 中国中药杂志, 2020, v.45(12):236-241.

5.  罗益远  刘娟秀  刘训红 等. 同基源何首乌和首乌藤化学成分含量分析[J]. 天然产物研究与开发  2016  28(7):1035-1044.

4.  王靖越  张语凡  柴冲冲 等. 何首乌饮片的颜色与蒽醌类和二苯乙烯苷含量的相关性研究[J]. 中南药学  2020(4).

3.  张语凡  王蕾  王鑫 等. 何首乌不同炮制时间与方式的薄层特征图谱鉴别[J]. 中华中医药杂志  2018  v.33(11):408-411.

2.  侯文文  石燕红  宋嬿 等. 一测多评法同步测定何首乌中4种蒽醌类成分的含量[J]. 中国中药杂志  2020  v.45(01):141-149.

1.  罗益远  刘娟秀  刘廷 等. UPLC-MS/MS法同时测定何首乌中二苯乙烯 蒽醌 黄酮及酚酸类成分[J]. 质谱学报  2016(4):327-335.

从2011年开始我们致力于在生命科学领域、生物医学实验技术及论文润色服务，协助客户各类实验服务及论文润色十多年，是您值得信赖的科研合作伙伴!

如果您受时间、试验条件等限制而无法完成您的课题研究，欢迎您与我们联系。

实验技术服务：